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KMID : 0387420110220040031
Korean Society of Oriental Neuropsychiatry
2011 Volume.22 No. 4 p.31 ~ p.39
A Review of Clinical Studies with Herbal Medicine for Depression - Based on Randomized Controlled Clinical Trial -
Lee Jae-Eun

Kwon Yong-Ju
Cho Seung-Hun
Abstract
Objective: This study aimed to investigate frequently used herbal materials among herbal prescription for depression focusing on randomized controlled trial.

Methods: Every article relevant to depression was initially obtained from China National Infrastructure(CNKI), Korean database and book hand-searching. Searching keywords were ¡¯depression¡¯, ¡¯herbal medicine¡¯ and ¡¯randomized controllled trial(RCT)¡¯.

Results: Among comorbidity with depression, the most accompanied disease was that of circulatory system. Among sixty-five articles, depression with cerebral vascular disease was twenty-eight. Article about mood disorder was twenty-four. High frequently used herbal materials were Bupleuri Radix(41times), Curcumae Radix(34 times), Acori Graminei Rhizoma and Cnidii Rhizoma(24 times).

Conclusion: According to this study, we could know select frequent-used herbal medicine. In a clinical treatment, herbal materials can be added herbal prescription related to depression. As these results, it can be helpful to develop new drugs.
KEYWORD
depression, herbal medicine, randomized controlled trial, Bupleuri Radix
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