KMID : 0387420110220040031
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Korean Society of Oriental Neuropsychiatry 2011 Volume.22 No. 4 p.31 ~ p.39
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A Review of Clinical Studies with Herbal Medicine for Depression - Based on Randomized Controlled Clinical Trial -
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Lee Jae-Eun
Kwon Yong-Ju Cho Seung-Hun
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Abstract
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Objective: This study aimed to investigate frequently used herbal materials among herbal prescription for depression focusing on randomized controlled trial.
Methods: Every article relevant to depression was initially obtained from China National Infrastructure(CNKI), Korean database and book hand-searching. Searching keywords were ¡¯depression¡¯, ¡¯herbal medicine¡¯ and ¡¯randomized controllled trial(RCT)¡¯.
Results: Among comorbidity with depression, the most accompanied disease was that of circulatory system. Among sixty-five articles, depression with cerebral vascular disease was twenty-eight. Article about mood disorder was twenty-four. High frequently used herbal materials were Bupleuri Radix(41times), Curcumae Radix(34 times), Acori Graminei Rhizoma and Cnidii Rhizoma(24 times).
Conclusion: According to this study, we could know select frequent-used herbal medicine. In a clinical treatment, herbal materials can be added herbal prescription related to depression. As these results, it can be helpful to develop new drugs.
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KEYWORD
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depression, herbal medicine, randomized controlled trial, Bupleuri Radix
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